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The Visible Genetic Map
of Human Chromosome 11
The Visible Genetic Map of Human Chromosome 11.
Thirty BACs for 27 STS markers on chromosome 11 were labelled with
one of six color combinations in groups of 1-3. All DNAs were hybridized
simultaneously and images were collected as described in the methods.
The STS order is shown for comparison to the FISH order that was confirmed
independently by both single and multicolor experiments. The green signals
for D11S4143 are obscured by overlying signals that appeared to suggest
a more distal location but were ordered by two color analyses. BACs for
markers D11S4107 and D11S4089 suggested multisite locations in q11.23
as shown.
Three randomly mapped BACs (J. R. Korenberg, X-N. Chen, Z. Sun, D. Noya,
H. Shizuya, M. Simon. in preparation) were used as markers for the telomeric
(B376B12; B1005B03) and centromeric (B344A05) regions.
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