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Clinical Trials

Cardiac Imaging Trials

Title: Cardiovascular Magnetic Resonance Imaging Database
Summary: The purpose of this study is to observe the way in which information from a cardiovascular MRI scan influences diagnosis and management of different cardiovascular illnesses, and how the results of the MRI might be useful in the prediction of future health in patients having the test. The study is also intended to help in developing better methods of analyzing cardiac MRI examinations. The collection of MRI scan result information into a database with many patients will allow observation of patterns within groups of people with the same cardiovascular illnesses. Comparison of the MRI results with patient's other cardiovascular imaging test results (such as echocardiograph, catheterization or CT scan results) will allow observation of what additional information was added by the MRI and whether the MRI result agreed with the results of other tests performed.

Title: CT-STAT
Summary: Coronary Computed Tomography for Systemic Triage of Acute Chest Pain Patients to Treatment (CT-STAT). This trial will compare the safety, diagnostic efficacy and efficiency of multi-slice computed tomography (MSCT) to the standard of care treatment of low to intermediate risk acute chest pain patients in the Emergency Department (ED).

Title: EISNER Study 1
Summary: The purpose of this study is to determine if a particular combination of assessments can predict future clinical outcomes in patients who have had no symptoms of coronary artery disease or other heart disease. The combination of assessments in this study includes medical history and risk factor information, a clinical exam, biochemical tests performed on a blood sample, and a cardiac CT imaging procedure.

Title: EISNER Study 2R - Any SPECT (non-randomized)
Summary: The primary purpose of this study is to determine if the information from a CT scan of the heart adds value to the information from the nuclear cardiology study in helping doctors make decisions about their patients medical care.

Title: EISNER Study 4- Database Project
Summary: The purpose of this study is to collect information from cardiac CT scans in the Imaging department to establish a large research database. The database information will then be used to conduct analyses and write manuscripts that will benefit physicians and their patients in the future and possibly lead to approval for insurance company reimbursement for the tests.

Title: GE I-mIBG Study
Summary: This study is to demonstrate the prognostic usefulness of assessment of myocardial sympathetic innervation, as determined by the heart to mediastinum (H/M) ratio on planar 123I mIBG imaging as either normal or abnormal, for identifying heart failure (HF) subjects at higher risk of experiencing an adverse cardiac event.

Title: Nuclear Cardiology Database Study
Summary: The purpose of this study is to establish a large research database including information from the nuclear cardiology test that is performed in the Imaging department. The database will be used to conduct important research analyses that we hope will benefit physicians and their patients.

For more on Cardiac Imaging Research Click Here

Imaging Trials

Title: Diffuson Tensor MR
Summary: The purpose of this study is to validate the ability of diffusion tensor imaging (DTI) and tractography to yield useful clinical information regarding disease progression or regression and response to treatment in patients suspected of having herniation of the cervical spine.

Title: RF Ablation in Patients with Liver Cancer and Hepatic Cirrhosis
Summary: The purpose of this research is to determine if percutaneous radiofrequency ablation (RFA) of the liver to treat hepatocellular carcinoma (HCC) in patients with cirrhosis is at least as effective as hepatic resection or liver transplantation.

Title: An Open-Label, Phase 2 Study to Assess the Safety and Efficacy of 99mTc-NC100697 Injection in Detecting or Excluding Striatal Dopaminergic Deficits in Subjects With 1 or More Signs of a Parkinsonian Syndrome. More information

Title: A Multicentre, Phase 1, Open-label, Non-Randomised Study to Determine the Striatal Uptake of 99mTc-NC100697_ Injection in Normal Human Volunteers Using Dual-Headed SPECT Cameras (TRO107). More information.

Title: Scintigraphic Swallow Evaluation (SSE)

Title: Potential Role of Statins in Memory Impairment
Summary: The purpose of this study is to demonstrate that statins may have an effect on blood flow in the brain and brain function which may be applied to further research on memory disorders.

Title: ACRIN 6678: FDG PET/CT to Evaluate Treatment Response in Non-Small Cell Lung Cancer Summary: The purpose of this clinical trial is to demonstrate that quantitative changes in FDG uptake during chemotherapy provides an early indication of the effectiveness of therapy in patients with advanced non-small cell lung carcinoma (NSCLC).

Title: Use of Pre-Operative PET/CT and USPIO MRI to Detect Abdominal Lymph Node Metastasis in Patients with Advanced Carcinoma of the Cervix.
Summary: This is a multicenter clinical trial to define the utility of pre-operative Combidex (iron-based contrast) MRI scanning and FDG-PET/CT scanning prior to chemoradiation to detect retroperitoneal (abdominal) lymph node metastasis in patients with locoregionally advanced cancer of the cervix.

 
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