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In 1999, Cedars-Sinai developed and received UNOS (United Network of Organ Sharing) certification for pancreas transplantation. Cedars-Sinai is one of a select few medical centers in Southern California performing kidney-pancreas transplants.

Pancreas transplantation is used to prevent or reverse secondary complications of diabetes. The treatment is reserved for patients who are undergoing kidney transplantation and are also Type 1 diabetic. Diabetic patients who have already undergone kidney transplantation are also candidates. The procedure is restricted to this patient population because pancreas transplantation alone is not a lifesaving procedure.