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Stem Cell Trials

Cedars-Sinai Heart Institute is currently conducting the following Stem Cell Trials:

  • Peritoneal Cavity Derived Stem Cells: A Pilot Study
  • The Cellular Origin of Cardiospheres and Cardiosphere-derived Cells (putative adult resident cardiac stem cells)


Peritoneal Cavity Derived Stem Cells: A Pilot Study

Principal Investigator: PK Shah, MD

IRB Approval Number: 11388

Contact: Linn Defensor, RN (310) 423-6034

Recruiting

Summary: The purpose of this study is to determine the genotype and phenotype characteristics of peritoneal cavity derived cells to determine whether stem cells are present in human peritoneal cavity. Peritoneal lavage fluid from patients who undergo elective open abdomen or laparoscopic surgery will be collected for this purpose. Additional medical information will be collected from each patient. Patients who are scheduled to undergo elective open abdomen or laparoscopic surgery are eligible to participate.

The Cellular Origin of Cardiospheres and Cardiosphere-derived Cells (putative adult resident cardiac stem cells).

Principal Investigator: Rajendra Makkar, MD

IRB Approval Number: 12121

Contact: Michelle Domingo (310) 423-3875

Recruiting

Summary: The purpose of this research study is to provide more information on a newly discovered type of heart stem-cells known as "cardiosphere" cells. It is not clear whether cardiosphere cells are intrinsic heart cells, or whether they "seed" into the heart from the circulation. This research will try to answer that question. Patients with a history of cardiac transplantation whose doctors recommend that they need a cardiac biopsy procedure can participate in this study.

 
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