Air Pollution and Brain Tumors

Principal Investigator: Julia Y. Ljubimova, MD, PhD

Air Pollution

Institute researchers were awarded a grant from the Southern California Air Quality Management District in 2004 to study the possible relationship between air pollution and brain tumors. The goal of this project is to study whether chronic exposure to air pollution results in molecular changes in the brain similar to those associated with the induction of brain tumors. Researchers wanted to determine whether differences in the size of ambient particles collected in the Los Angeles basin in California, such as coarse (2.5-10 micron), fine (< 2.5 micron) and ultra fine (< 0.1 micron) particulate matter (PM) could be related to changes in gene expression in rat brains similar to that seen during tumor development.

Grant Support

Brain Tumor and Air Pollution Foundation Grants 07/01/04-06/30/08

NIH/NCI R01 CA 123495 (08/01/06-07/31/11)

Nanotechnology Characterization Laboratory (NCL/NIH)

Department of Neurosurgery, Cedars-Sinai Medical Center

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