Research is an ongoing process at the Cedars-Sinai Pituitary Center. Scientists at Cedars-Sinai are doing research that expands our knowledge of pituitary tumors -- how they begin, how they grow and how best to treat them.

The Cedars-Sinai Pituitary Center is conducting the following clinical trials:

• The global hypopituitary control and complications study. (IRB #4083. Principal Investigator: Shlomo Melmed, MD)
• A study to compare the safety, efficacy and pharmacokinetic/pharmacodynamic relationship of multiple doses of SOM 230 and doses of open label Sandostatin in acromegalic patients. (IRB #4337. Principal Investigator: Shlomo Melmed, MD)
• A study to explore the natural course of disease for non-functioning microadenomas and non-functioning macroadenomas. (Pro9829. Principal Investigator: Shlomo Melmed)
• Effectivness of SOM230 in treating non-functioning pituitary tumors. (IRB # 4291. Principal Investigator: Shlomo Melmed, MD)
• Does surgical debulking of pituitary adenomas improve responsiveness to Octreotide LAR in the treatment of acromegaly: an investigator-initiated study. (IRB #4276. Principal Investigator: Shlomo Melmed)
• A study examining the peri- and post-operative dynamics of the GH/IGF-1 axis in subjects with acromegaly during the first year after surgical resection. (Pro8997. Principal Investigator: John D. Carmichael, MD)
• Laser fluorescence of brain tumors. (IRB #3444. Principal Investigator: Adam Mamelak, MD)
• Prevalence of pituitary incidentaloma in relatives of patients with pituitary adenoma. (IRB #3765. Principal Investigator: Vivien Bonert, MD)